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Organic anion transporter protein

Witryna3 wrz 2024 · DTU Biosustain. +45 45 25 80 20. Scientists discover the secret behind some protein transporters’ superiority. One transporter, MAE1, can export organic acids out of yeast spending close-to-zero energy. Organic acids are utilized as building blocks for plastic and rubber, and the finding could become important in industrial … Witryna9 cze 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys …

The multispecific organic anion transporter family: properties and ...

Witryna6 sie 2024 · Organic anion transporter (OAT) 2 and OAT7 were recently shown to be involved in the hepatic uptake of drugs; however, there is limited understanding of the … Witryna29 mar 2024 · This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the … sparks lunch spots https://asouma.com

Why transporters really matter for cell factories - DTU Biosustain

WitrynaObjectives: Recent reports indicated that reduced SLC22A7 (a gene-encoding organic anion transporter 2) expression in noncancerous liver tissue predicts hepatocellular … WitrynaThese organic anions are transported from the blood into the endothelial cells of the renal proximal tubules by the OAT1 transporter. From there, these waste molecules … Witryna9 wrz 2016 · Our approach should provide novel mechanistic insights into the role of OAT1 and other drug transporters implicated in metabolic diseases like gout, … sparks lyrics this town isn\u0027t big enough

Molecular Mechanism of Ochratoxin A Transport in the Kidney

Category:Organic anion transporter 1 - Wikipedia

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Organic anion transporter protein

solute carrier organic anion transporter family, member 3a1

WitrynaView/Edit Human. Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 gene. [3] [4] Pharmacogenomic research indicates that genetic variations in this gene are associated with response to simvastatin. [5] Clinical guidelines exist that can guide dosing of simvastatin based on … WitrynaOfficial Symbol : SLCO3A1 Official Name : solute carrier organic anion transporter family, member 3A1 EnsemblGene ID : Other Names : solute carrier family 21 (organic anion transporter), member 11, OATPRP3, FLJ40478, OATP3A1, solute carrier organic anion transporter family member 3A1, PGE1 transporter, SLC21A11, …

Organic anion transporter protein

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Witryna13 lut 2024 · Abstract. Organic anion transporter 3 (OAT3) plays a vital role in removing a broad variety of anionic drugs from kidney, thus avoiding their possible … Witryna24 paź 2024 · DOI: 10.3390/ijms20245303 Abstract Renal drug transporters such as the organic cation transporters (OCTs), organic anion transporters (OATs) and …

Witryna29 mar 2024 · This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri … WitrynaAbstract. 1. Organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 are polyspecific transporters that mediate the transport of organic acids into …

Witryna26 wrz 2011 · Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and … WitrynaSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the …

Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the Solute Carrier Family (SLC) and the major facilitator superfamily.

WitrynaAbstract. The members of the organic anion transporter (OAT) family are mainly expressed in kidney, liver, placenta, intestine, and brain. These transporters play … techinclicWitrynaTransporter proteins are integral membrane proteins that catalyze transfer of solutes across plasma membranes at faster rates than would occur by diffusion. Transporter proteins are a large and diverse group of molecules generally characterized by showing substrate specificity. ... Organic anion–transporting polypeptides (OATPs), encoded … sparks loyalty loginWitrynaOfficial Symbol : SLCO3A1 Official Name : solute carrier organic anion transporter family, member 3A1 EnsemblGene ID : Other Names : solute carrier family 21 … sparks machine