WebBesen Sanga, Madan K. Kharel, in Reference Module in Biomedical Sciences, 2024. Background (significance/history) Chloramphenicol was first isolated from cultures of the soil bacterium Streptomyces venezuelae in 1947 but is now produced synthetically. Due to its broad-spectrum coverage against Gram-positive and Gram-negative bacteria, the … Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. Its use by mouth or by injection is only recommended when … See more The original indication of chloramphenicol was in the treatment of typhoid, but the presence of multiple drug-resistant Salmonella Typhi has meant it is seldom used for this indication except when the organism is known … See more Chloramphenicol is extremely lipid-soluble; it remains relatively unbound to protein and is a small molecule. It has a large apparent See more Chloramphenicol was first isolated from Streptomyces venezuelae in 1947 and in 1949 a team of scientists at Parke-Davis including Mildred Rebstock published their identification of the … See more Although its use in veterinary medicine is highly restricted, chloramphenicol still has some important veterinary uses. It is currently considered the most useful treatment of chlamydial disease in koalas. The pharmacokinetics of chloramphenicol have been … See more Aplastic anemia The most serious side effect of chloramphenicol treatment is aplastic anaemia. This effect is rare but sometimes fatal. The risk of AA … See more Chloramphenicol is a bacteriostatic agent, inhibiting protein synthesis. It prevents protein chain elongation by inhibiting the peptidyl transferase activity … See more Names Chloramphenicol is available as a generic worldwide under many brandnames and also under various generic names in eastern Europe and Russia, including chlornitromycin, levomycetin, and chloromycetin; the … See more
Chloramphenicol - Wikipedia
WebFeb 25, 2014 · Most isolates were susceptible to antibiotics recommended for treating Vibrio infections, although the majority of isolates expressed intermediate resistance to chloramphenicol (78% of V. vulnificus, 96% … WebJan 6, 2024 · Chloroptic (Chloramphenicol) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug … fertility calendar ovulation calculator
Chloramphenicol: Antibiotic Uses, Warnings, Side Effects, Dosage
WebNational Center for Biotechnology Information WebDec 15, 2005 · It is rapidly bactericidal against S. aureus in vitro; approved for adults with complicated skin and soft-tissue infections 14; highly bound to serum proteins but has poor penetration in lung... WebChloramphenicol injection is used to treat certain types of serious infections caused by bacteria when other antibiotics cannot be used. Chloramphenicol injection is in a class … dell install windows on new ssd